Calibrin®-Z Biotoxin Control | Amlan International

Calibrin-Z Defends the Intestinal Barrier from the Broadest Spectrum of Biotoxins

Protects poultry and livestock from biotoxins that reduce health and performance
Binds bacterial exotoxins and endotoxin
Binds polar and nonpolar mycotoxins
Consists of a single ingredient: our proprietary mineral technology
Low-dose design for use in poultry, swine, aquaculture and dairy feed

Product availability may vary by country; associated claims do not constitute medical claims and may differ based on government requirements.

Increases Weight Gain

Improves Intestinal Health and Function

Increases Feed Efficiency

Binds Multiple Exotoxins and Mycotoxins

Over 70 Studies Confirm the Biotoxin Control and Performance-Improving Abilities of Calibrin-Z

Biotoxin-Binding Advantages of Calibrin-Z

The specific structural properties of Calibrin-Z, together with a proprietary thermal-processing method, promote biotoxin binding and help prevent intestinal absorption of mycotoxins and bacterial toxins.

Fungal Biotoxin Binding Using Observed Levels in Feed (% Adsorbed)

Source: Trilogy Analytical Laboratory, USA.

In Vitro E. coli Heat Labile Toxin Adsorbtion (% Adsorbed)

Source: USDA-ARS, Beltsville, MD.

In Vitro E. coli Shiga-Like Toxin Adsorbtion (% Adsorbed)

Source: USDA-ARS, Beltsville, MD.

In Vitro C. perfringens Toxin Adsorbtion (% Adsorbed)

Source: USDA-ARS, Beltsville, MD.

E. coli Endotoxin Binding (% Adsorbed)

Source: Gilbraltar Laboratories, Fairfield, NJ.

In Vitro Binding of C. difficile Toxins by Calibrin-Z (% Adsorbed)

Source: USDA, Beltsville, MD.

In Vitro Vibrio parahaemolyticus Toxin Adsorption (% Adsorbed)

Source: National Cheng Kung University, Taiwan.

Calibrin-Z Binds Multiple Mycotoxins and Bacterial Biotoxins

Independent laboratories have verified that Calibrin-Z effectively binds the following mycotoxins and bacterial exotoxins and endotoxin in vitro:

Polar mycotoxins: aflatoxin, ergotamine, ergovaline and cyclopiazonic acid
Nonpolar mycotoxins: T-2 toxin, fumonisin, ochratoxin and zearalenone
Clostridium perfringens alpha-toxin and NetB toxin
Escherichia coli heat-labile and Shiga-like toxins and lipopolysaccharide (LPS)
Clostridioides difficile (previously Clostridium difficile) toxin A and toxin B
Vibrio parahaemolyticus PirA and PirB toxins

Minimize Mycotoxin Risk With BioInsights

Our BioInsights Mycotoxin Diagnostic Service helps minimize the effects of mycotoxin-contaminated feed that can severely impact the health and productivity of a flock or herd. BioInsights enables on-site feed ingredient testing — accurately identifying and quantifying mycotoxins within minutes, then recommending the most effective dose of Calibrin-Z to mitigate the mycotoxin contamination.

Extensive Research Proves Calibrin-Z Works

Calibrin-Z is one of the most comprehensively researched solutions for controlling a wide range of biotoxins that reduce animal performance. We have collaborated with leading contract research organizations, respected universities and large-scale commercial producers to prove the production and intestinal health benefits of Calibrin-Z.

Effect of purified zearalenone with or without modified montmorillonite on nutrient availability, genital organs and serum hormones in post-weaning piglets.

Quorum Sensing Disruption in Vibrio harveyi Bacteria by Clay Materials.

Preventing Biotoxins With Mineral Technology