NeutraPath® Natural Pathogen Control

Natural Pathogen Control Designed to Provide Equivalent Performance to In-Feed AGPs in High-Challenge Environments

Exhibits bacteriostatic and bactericidal properties
Neutralizes bacterial toxins
Disrupts quorum sensing (bacterial communication)
Improves intestinal health
Proprietary and co-active blend of essential oils, fatty acids and our proprietary mineral technology

Product availability may vary by country; associated claims do not constitute medical claims and may differ based on government requirements.

A Proven Natural Solution to Bacterial Pathogens: Learn More About NeutraPath’s Several Modes of Action

Reduces Pathogenic Bacterial Load and Colonization

Improves Performance of Pathogen-Challenged Poultry and Livestock

Reduces Mortality

Improves Intestinal Health

NeutraPath Has a Proven Synergistic Formula With Multiple Modes of Action

Bactericidal and Bacteriostatic Effects of NeutraPath

By binding pathogenic bacteria, NeutraPath reduces pathogen colonization of the gastrointestinal tract. However, NeutraPath also has multiple bactericidal and bacteriostatic effects. For example, by disrupting pH homeostasis and increasing membrane permeability, NeutraPath impairs bacterial cell function and integrity. NeutraPath also compromises pathogen purine integrity and binds to a protein essential for bacterial cell division, both of which prevent bacterial replication.

Reduces Pathogenic Bacterial Load and Colonization

Improves Performance of Necrotic Enteritis Challenged Broilers

Improves Intestinal Health and Reduces Mortality

Unbound C. perfringens-Produced Alpha-Toxin

A 4-fold reduction in unbound C. perfringens-produced alpha-toxin occurred in cecal contents of challenged broilers fed NeutraPath compared to challenged control birds (128 total birds). Source: Southern Poultry Research, Inc. Athens, GA.

NeutraPath Neutralizes Bacterial Virulence Factors

The virulence of bacterial pathogens is determined by multiple factors, many of which NeutraPath can neutralize. NeutraPath can bind the toxins produced by pathogenic bacteria as well as the quorum-sensing molecules used by bacteria to communicate and coordinate their attack. Virulence genes can also be targeted — in one study, NeutraPath downregulated expression of Salmonella enterica serovar Typhimurium genes that encode the host cell invasion system.

NeutraPath Mode of Action Throughout the Gastrointestinal Tract

When first ingested, NeutraPath is at or above the minimum inhibitory concentration (MIC). In the upper GI tract, the bactericidal and bacteriostatic effects of NeutraPath target bacterial cell structure and function. In the lower GI tract, NeutraPath’s antivirulence actions provide the main antimicrobial effects.

In Necrotic Enteritis-Challenged Broilers NeutraPath Reduced Necrotic Enteritis-Caused Mortality

Source: Southern Poultry Research, Inc. Athens, GA. (240 Total Birds).

In Necrotic Enteritis-Challenged Broilers NeutraPath Reduced Ileal C. perfringens Populations Compared to the Challenged Control

Source: Southern Poultry Research, Inc. Athens, GA. (224 Total Birds).

NeutraPath Improved Commercial Broiler Performance

Source: Side-by-side commercial broiler houses for an integrated broiler producer in the Southern United States. 54,000 birds per house.

Serum Corticosterone Levels

Source: Side-by-side commercial broiler houses for an integrated broiler producer in the Southern United States.

NAE Broiler Program Performance and Stress Levels Improved with NeutraPath

In a broiler study using side-by-side commercial houses, NeutraPath improved key performance indicators. NeutraPath-fed birds also had lower serum corticosterone levels, indicating lower stress levels.

NeutraPath Improves Performance of Necrotic Enteritis-Challenged Broilers

The antimicrobial effects of NeutraPath allow better absorption of nutrients and improved intestinal health in challenged environments. We have collaborated with leading contract research organizations and well-known universities to prove that these antimicrobial effects of NeutraPath translate into production and health benefits.

Day 0-28 Feed Conversion Ratio