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Global Perspectives on Feed Additive Technologies

FeedStuffs interview with Amlan logo graphic.

Source: Sarah Muirhead, Feedstuffs 365, January 26, 2022

During IPPE 2022 in Atlanta, Georgia, Sarah Muirhead from Feedstuffs 365 spoke with Amlan leadership about global poultry production trends and the background of Amlan’s natural mineral-based products. During the discussion, Dan Jaffee, President and CEO, Oil-Dri Corporation of America and President and General Manager of Amlan International, described the history of Amlan and the origin of the mineral that is the core of Amlan products.

Other discussion topics included global trends Fred Kao, VP of Global Sales, is observing in the poultry industry. Fred spoke about the increase in antibiotic-free poultry production in Brazil as producers adjust to new EU export requirements and the impact that African Swine Fever has had on poultry product demand in Asia.

Dr. Wade Robey, VP Global Marketing and Product Development, also detailed the benefits of two new Amlan products that were launched at IPPE (International products, not for sale in the US). One product is intended for application in antibiotic-free broiler production when pathogens are decreasing bird performance or when producers are trying to reduce pathogen levels entering the processing plant (NeutraPath®), and the other is a natural alternative to anticoccidial drugs and vaccines (Phylox®) for full time use or in a shuttle program when resistance to traditional coccidiostats is a concern. Both products also have excellent application potential in broiler breeders which are often challenged with coccidiosis and which can be very sensitive to mycotoxins and bacterial pathogens during grow-out and egg production.

Watch the interview here.

Amlan International North American Product Portfolio Meets Producer Needs

Amlan North American products with logos text graphic.

Amlan International is excited to offer our North American customers an exclusive portfolio of mineral-based feed additives that support gut health and improve the sustainability of poultry and livestock production. The North American portfolio expands our efforts to support optimal intestinal health in protein-producing animals around the world.

Consumers in North America, like global consumers, demand high-quality animal protein raised without antibiotics. These consumer preferences, coupled with concerns about microbial resistance, have put producers under pressure to reduce the use of in-feed antibiotics. Consequently, North American producers and vertical integrators are seeking cost-effective, non-antibiotic, natural feed additives that support feed conversion and optimal intestinal health. Their search ends with our North American product range that can help with these challenges.

Our mineral-based feed additives offer multiple advantages for animal protein producers. The products support optimal gut health and meet the demands for cleaner food while reducing the inputs needed to raise production animals, helping to decrease the cost and environmental impact of poultry and livestock production.

Our North American sales and technical service team, led by Heath Wessels, Director of Sales and Technical Service for North America, is eager to partner with top-tier producers to help them achieve their production goals by integrating Amlan products into their operations. “Our natural feed additives are formulated to have strong synergy with each other for supporting optimal gut health,” said Heath. “We offer individual product solutions or can recommend product combinations for maximum results.”

The new product line will only be available for sale in North America but will be offered with the same excellence and reliability that global producers know and trust from our international product offerings. Amlan is vertically integrated as the animal health business of Oil-Dri® Corporation of America, allowing Amlan and Oil-Dri to control every step of the production process and reliably deliver safe, high-quality single-sourced products from company-owned mines.

The North American product portfolio strengthens our commitment to leading the industry in supplying natural feed additives that support animal intestinal health and add value for producers. Meet our products below, and if you have any questions about our North American product portfolio, please contact info@amlan.com.

Amlan North American Product Portfolio Text Graphic | Amlan International

Complete Control Over Mineral Supply Safeguards the Quality of Amlan International Products

Infographic advertising Amlan’s 80-plus year mineral science expertise and their company values.

As the animal health business of Oil-Dri® Corporation of America, Amlan International’s scientifically proven products are backed by Oil-Dri’s 80+ years of experience in mineral science. Amlan has access to the hundreds of millions of tons of mineral reserves that Oil-Dri, based and operating in the USA, selectively mines, processes and sells in a diverse range of industries throughout the world. Vertical integration allows Oil-Dri and Amlan to own every step of the production process and consistently deliver reliable non-medicated solutions to support animal protein producers around the world as they look to optimize animal health and production economics.

Safe Thermal Processing

The single-source raw material used in Amlan products is an all-natural mineral ingredient that contains high-capacity opal-CT lepispheres. This mineral is selected because its properties allow for thermal processing that is specifically talilored for each product. Thermal processing ensures the minerals’ structural integrity and optimizes the products’ broad utility, ultimately helping producers achieve normal animal health and meet their production goals.

Independent Assessments for Regulatory Requirements

Each quarter, all Amlan product lots are assessed by an independent laboratory to ensure they comply with regulatory requirements. These analyses ensure the mineral is below any established regulatory levels for dioxins (PCDD/F+PCB) and heavy metals (lead, cadmium, arsenic and mercury) in feed or food. This report is available upon request by contacting info@amlan.com. For both performance and safety, Amlan also performs extensive core drilling analyses of their raw material and selectively mines the highest quality raw materials for use in their products.

High-Quality Manufacturing Standards

All Amlan products are made to the highest industry standards for non-medicated feed additives to ensure their safety and consistent performance. Amlan’s quality systems are audited and certified annually by independent parties to demonstrate compliance.

Approved Feed Ingredients Only

Amlan’s feed additives only use ingredients that are approved for use in feed products by major regulatory bodies such as the U.S. FDA or the EU. This helps to secure the safety of the animal and, as Amlan’s products are developed for protein-producing animals, ensures end consumers are safe too. Amlan is proud to carry the Organic Materials Review Institute (OMRI) seal of approval on many of its products. OMRI Listed® products are approved for use in certified organic operations under the USDA National Organic Program.

High-Quality, Safe Products Are Paramount

Along with following ISO-9001 standards and a certified HACCP system, Amlan is also a certified International Safe Feed/Safe Food plant. This voluntary and independently certified program designed for the total feed industry establishes comprehensive standards of excellence that go beyond existing regulations to maximize food and feed safety. This certification assures customers that Amlan’s products are safe, healthy, trustworthy feed solutions. For all applicable products and production facilities, Amlan also meets the requirements set forth by FAMI/QS — a certification created exclusively for specialty feed ingredients and their mixtures. Many countries require the FAMI/QS certification to sell market specialty feed ingredients within their borders.

Mineral Technology Is the Amlan Difference

Amlan’s proprietary mineral technology is the foundation of their innovative products. In fact, multiple governments, including the United States, the European Union, China, Korea and Indonesia have recognized the unique mineral-based technology within Amlan’s products Varium® and NeoPrime® and have issued a patent for the products’ modes of action.

By leveraging their owned, unique mineral technology and committing to the highest quality standards, Amlan develops innovative and reliable natural, mineral-based feed additive solutions for poultry and livestock. To learn more about Amlan’s products, visit https://amlan.com/products/.

Scientific Expertise and a State-of-the-Art Facility: The Foundation for Developing Amlan’s Natural and Efficacious Products

Still image from INNOVATION NATION interview with Dr. Hongyu Xue MD, PhD, at Research Laboratory.

With cutting-edge equipment and state-of-the-art facilities, Amlan’s talented Life Sciences team creates value-adding mineral-based products for poultry and livestock producers. The Richard M. Jaffee Center for Applied Microbiology houses the specialized equipment used by the Life Sciences team who draw upon their extensive research experience and knowledge base to create novel, natural solutions that improve poultry and livestock health and production efficiency.

Life Science Experts

The Amlan research team is led by Life Sciences Director Hongyu Xue MD, PhD, an experienced scientist in clinical and animal nutrition, who brings a unique point of view to Amlan’s research by leveraging his expertise in human medicine. Dr. Xue has a background in academic medicine and research that cross-links gastroenterology, immunology, microbiology and nutrition. Working with Dr. Xue is a multi-disciplinary team of scientists with expertise across microbiology, animal nutrition, chemistry and material science areas. Several members of the Life Sciences team were recently featured on an episode of “Built in America: INNOVATION NATION” on the Fox Business Network, where they showcased some of their novel research.

Cutting-Edge Equipment

The state-of-the-art equipment in the Richard M. Jaffee Center for Applied Microbiology allows the Life Sciences experts to use a variety of research techniques to develop and assess new mineral-based products for the animal health market.

The Life Sciences team enhances Amlan’s unique mineral to develop natural solutions that can control the microbial pathogens that negatively impact the health and productivity of poultry and livestock. To do this, the scientists study these pathogens and their toxins to understand their physiology and mode of action. Some pathogens require anerobic conditions to survive, so these pathogens are cultivated in Amlan’s anerobic chamber — a more efficient and robust method than alternative techniques such as anerobic jar or pouch systems.

Conditions within the chamber can perfectly mimic the anerobic environment of the distal gastrointestinal (GI) tract (e.g., ileum and cecum) which serves as the primary colonization site for a vast variety of common microbial pathogens for poultry and livestock. The anaerobic chamber is of tremendous value to help Amlan’s scientists cultivate and further characterize the target pathogens and select commensal microbial populations colonizing the distal GI tract. Further, the chamber also enables the scientists to screen novel products in development and evaluate their antimicrobial effects for certain anaerobic pathogens. Novel strains of beneficial bacteria (probiotics) can also be isolated, grown and tested in the anerobic chamber. The photo below shows an example of the zone of inhibition surrounding an Amlan-developed probiotic (right) versus a water control (left).

Close-up of petri dish.

Further assessment of the new products can be conducted using equipment such as an ICP-OES (inductively coupled plasma-optical emission spectrometer) that allows the team to examine how different cations released by Amlan’s unique mineral affects bacterial virulence. Some metals (cations) are known to suppress the expression of virulence genes in bacterial pathogens.

The lab also includes a fluorescent microscope that enables microbes to be observed instantly to see a product’s effect on bacterial morphology and viability.

Using real-time polymerase chain reaction (PCR), the Life Sciences team have developed methods to detect toxin genes from microbial pathogens that can have negative effects on poultry and livestock production. Using this information, natural solutions can be developed that disarm these pathogens and help protect birds and animals from disease. For example, real-time PCR is used to investigate the effects of new products on pathogen virulence gene expression. Further, this technology can help determine the copy numbers of specific virulence genes and help make an early diagnosis of specific enteric diseases in poultry and livestock.

The Richard M. Jaffee Center for Applied Microbiology is named after the former chairman of Oil-Dri Corporation of America, doing business as Amlan International. Jaffee’s pioneering spirit and vision for Oil-Dri to conduct research in the life sciences is the influence behind Amlan’s focus on developing value-added next-generation animal health products.

To learn more about the research behind Amlan’s natural and efficacious products, visit https://amlan.com/blog/category/research-studies/.

The Benefits of Pelleting Feed and Related Diet Considerations

Close-up of large metal poultry feeder.

The benefits of pelleting feed have been an area of interest for decades; however, recent research suggests that the extent of the performance improvements may depend on other diet characteristics. With feed estimated to be around 70% of production costs for poultry and swine producers, the benefit-cost ratio is an important factor when determining what form the diet should take.

Pellet Quality

Pelleting can improve production performance, although research has found that this can depend on the quality of the pellet. Positive production effects can be limited if the pellet quality is poor and there is a large percentage of fines in the feed. In a broiler study,1 an improvement in feed intake, live weight gain, feed conversion rate (FCR) and carcass weight was observed as the percent of pellets in the feed increased. A model based on this research indicated a 0.4-point increase in FCR, a 10 g carcass-weight increase and a 4 g breast-weight improvement for every 10% increase in intact pellets in the feed.

Pellet and Nutrient Density Relationship

The extent of production improvements from pelleting may also depend on the diet formulation. Recent research suggests that the level of nutrient density may determine how beneficial pelleting really is. In two broiler studies,2,3 five diet nutrient density levels were compared in either mash or pellet form. As expected, broilers fed pelleted diets had better performance than mash-fed birds at all nutrient density levels. However, the pellet benefits were greater at the lowest nutrient density and positive performance responses to pelleting decreased as nutrient density increased. Therefore, the nutrient density of diets may be an important consideration during diet formulation to ensure that the extra expense of pelleting delivers the expected increase in performance.

Mitigating Mycotoxin Effects

Another potential benefit of pelleting feed is the reduction of negative performance effects observed when feed is contaminated with the mycotoxin deoxynivalenol (DON). In two swine studies,4,5 pelleting DON-contaminated diets improved average daily gain and gain to feed (G:F), ameliorating the reduction in performance caused by DON-contaminated feed. The concentration of DON in the diet was not altered by pelleting, but the performance benefits of pelleting were able to mitigate the DON-related production losses. Numerically, the increase in daily gain due to pelleting was greater in the DON-contaminated feed than the control feed. It is not clear however, if negative effects from contamination by other mycotoxins could also be abated by pelleting, so using a natural mycotoxin control product is recommended. To identify if feed is contaminated with mycotoxins and at what concentration, BioInsights Mycotoxin Diagnostic Services, offered by Amlan International, can test feed on-site and provide an accurate quantitative result within 10 minutes.

Other Benefits of Pelleting

Pelleting can increase palatability by masking unpleasant ingredient tastes and reducing ingredient sorting. Production efficiencies also improve as less feed is wasted and time allocated to eating is reduced, which allows more energy to be dedicated to growth.

Pelleting feed has multiple logistic benefits including improving feed flow through bins and less space required for storage. Ingredient separation during storage and transport and dust production are also reduced — depending on the quality of the pellet. Low-quality pellets that have a large percentage of fines may still have these issues.

Pelleting feed has many potential advantages, as long as all components of the diet formulation are considered, pellet quality is maximized and the pellets, like all feed, are manufactured safely following recommended guidelines.

References

  1. Lilly K, Gehring C, Beaman K, Turk P, Sperow M, Moritz J. Examining the relationships between pellet quality, broiler performance, and bird sex. J Appl Poult Res. 2011;20:231–239. https://doi.org/10.3382/japr.2009-00138
  2. Abdollahia M, Zaefariana F, Ravindrana V, Selleb P. The interactive influence of dietary nutrient density and feed form on the performance of broiler chickens. Anim Feed Sci Technol. 2018;239:33–43.
    https://doi.org/10.1016/j.anifeedsci.2018.03.005
  3. Hamungalu O, Zaefarian F, Abdollahi M, Ravindran V. Performance response of broilers to feeding pelleted diets is influenced by dietary nutrient density. Anim Feed Sci Technol. 2020;268:114613
    https://doi.org/10.1016/j.anifeedsci.2020.114613
  4. Frobose H, Fruge E, Tokach M, Hansen E, DeRouchey J, Dritz S, Goodband R, Nelssen J. The effects of deoxynivalenol-contaminated corn dried distillers grains with solubles in nursery pig diets and potential for mitigation by commercially available feed additives. J Anim Sci. 2015;93:1074–1088. https://doi.org/10.2527/jas.2013-6883
  5. Frobose H, Fruge E, Tokach M, Hansen E, DeRouchey J, Dritz S, Goodband R, Nelssen J. The influence of pelleting and supplementing sodium metabisulfite (Na2S2O5) on nursery pigs fed diets contaminated with deoxynivalenol. Anim Feed Sci Technol. 2015;210:152–164. https://doi.org/10.1016/j.anifeedsci.2015.09.020

Exploring Necrotic Enteritis: Cause, Effects and Solutions

Computer-generated illustration of necrotic enteritis.

Necrotic enteritis is a common infectious disease that costs the poultry industry billions of dollars each year. With more and more poultry production systems moving toward the global objective of reduced in-feed use of antibiotics for growth promotion, maintaining a healthy intestinal environment now relies more heavily on other management methods to reduce the risk of necrotic enteritis development. Keep reading to learn more about the origins of necrotic enteritis, the relationship between necrotic enteritis and coccidiosis, and management of the disease risk in ABF production systems.

C. perfringens: The Cause of Necrotic Enteritis

Necrotic enteritis is caused by Clostridium perfringens types A and C: gram-positive, spore-forming anerobic bacteria. C. perfringens can be found throughout the poultry house environment and has spores which, under the right environmental conditions, can survive for long periods outside the bird. The normal microbiota of the bird contains C. perfringens, so its presence alone doesn’t necessarily indicate an issue. Instead, disease occurs when predisposing conditions in the bird cause overgrowth of the pathogen. There are multiple factors that can contribute to C. perfringens overgrowth including diet changes, immune status and stress, intestinal pathophysiology and concurrent infection with coccidiosis.

Multiple exotoxins can be produced by C. perfringens, including alpha-toxin and necrotic enteritis toxin B-like toxin (NetB). Alpha-toxin is cytotoxic to endothelial cells, red blood cells, white blood cells and platelets, whereas NetB toxin forms pores in cell membranes that allows electrolytes to rupture cells, causing cell death and necrotic lesions in the small intestinal mucosa. These two toxins are known to have a role in necrotic enteritis development.

Impaired Nutrient Adsorption

In healthy birds, the epithelium and mucus layer of the intestine form a selective barrier between internal tissues and the external environment (the intestinal lumen). The natural barrier allows nutrients through the intestinal wall but not pathogens and their biotoxins. When there is an overgrowth of C. perfringens, there is a breakdown of the defensive barrier. The damage to the intestinal wall hinders nutrient digestion and absorption and can allow toxins to enter the circulatory system.

Necrotic enteritis can present as either clinical or subclinical disease. The clinical form is characterized by high mortality, whereas subclinical disease causes decreased weight gain and increased feed conversion ratio (FCR). The increased FCR is due to the reduced nutrient digestibility and adsorption, resulting in compensatory feed intake.

Coccidiosis Can Increase Necrotic Enteritis Incidence

Coccidiosis is another common disease in poultry that causes a significant negative economic impact on production. It is an enteric disease caused by parasitic protozoa in the Eimeria genus. Part of the Eimeria life cycle includes invading intestinal epithelial cells, damaging the intestinal wall barrier. The damage that coccidia cause to intestinal epithelial cells promotes invasion by C. perfringens (as well as other pathogens), increasing the incidence of necrotic enteritis.

Necrotic Enteritis in Antibiotic-Free Production

Managing necrotic enteritis in an ABF production system requires detailed strategies including the use of vaccinations, diagnostic tools and natural feed additives. In some production systems, ionophores used to control coccidiosis may also be eliminated, which further heightens the importance of other management practices that keep birds free of diseases like coccidiosis and necrotic enteritis.

Management practices, such as biosecurity, sanitation, water quality and air quality, also require increased planning and monitoring in ABF systems. Reduced ventilation, increased litter moisture and poor husbandry can increase the incidence of necrotic enteritis. The quality and sanitation of eggs in the hatchery also needs to be managed well in ABF systems, so that birds have a healthy start to life.

Necrotic Enteritis Control Solutions

Along with management best practices, natural feed additives such as Varium® and Calibrin®-Z are available to help reduce the incidence of necrotic enteritis. Varium, a natural patented mineral-based feed formulation, can reduce challenges from pathogenic bacteria and their toxins, strengthen the intestinal barrier and activate the innate immune system to naturally defend against disease. In high challenge environments, Calibrin-Z, a broad spectrum biotoxin control feed additive, can be used on top of Varium to reduce the level of pathogens in the intestines that cause mortality, wet droppings, reduced feed efficiency and damage the integrity of the intestine.

Necrotic enteritis is a challenging disease for poultry producers, particularly those using an ABF production system. However, with best practice management strategies and inclusion of feed additives that promote intestinal health and function, poultry flock health can be improved, thereby reducing the risk of disease and maximizing production efficiency. To learn more about necrotic enteritis, keep checking the Education Center for other posts in the necrotic enteritis series.

Reference

Chi, F. A Viable Adjunct or Alternative to Antibiotics: Meta-Analysis of Broiler Research Shows Natural Growth Promoter Delivers Feed Efficiency Equal to Antibiotics, Amlan International. https://amlan.com/product-category/feed-efficiency/

ABF Poultry Production Best Practice Series: Air Quality

Antibiotic-free poultry air quality infographic.

An effective poultry house ventilation system is essential for keeping litter dry, ammonia levels low and creating an environment that promotes healthy and efficient birds. This also includes managing the temperature and humidity to keep birds near their thermoneutral zone which will help drive weight gain and maximize feed conversion. Here, we take a closer look at what our industry experts consider air quality best practices for antibiotic-free poultry producers, as part of our series on strategies for producing antibiotic-free poultry.

Achieve Low Moisture and Ammonia Levels

Removing moisture from the poultry house is key for birds that are healthy and performing at their potential. Maintaining air movement, with fresh air coming in and stale air moving out, helps keep the floors and litter dry. As mentioned in our previous post on house environment and biosecurity, dry litter reduces the risk of disease and helps ammonia stay at acceptable levels.

Monitoring ammonia levels is an important factor for protecting bird health. If ammonia levels are too high it can irritate the birds’ nasal passages, trachea and eyes and cause dermatitis in paws, leading to poor performance. To keep birds safe, electrochemical, colorimetric or dosimeter tubes are available to monitor ammonia levels. Products can also be added to the litter to help minimize ammonia concentration, but keeping the litter dry (e.g., no leaking water lines) and providing adequate air flow and ventilation are important first steps.

Wet droppings due to poor intestinal health can also contribute to increased moisture and ammonia levels in the litter. Preventing enteric diseases, such as coccidiosis and necrotic enteritis, can help reduce the occurrence of diarrhea or wet droppings. Enteric diseases were traditionally controlled by antibiotics, but with the increase in antibiotic free production, natural alternatives are now available that can help maintain intestinal health and integrity.

Maintain Thermoneutral Zone

Birds should be kept near their thermoneutral zone so that they are not cold or heat stressed and are better able to cope with other stress, such as pathogens in the environment. Controlling air temperature and humidity in the house is a large task as not only does the weather impact them, the birds themselves put out their own BTU which contributes to the overall heat and moisture in the house.

If available, controllers can program fans and heating systems to try to maintain the temperature and humidity within a set range for the birds’ age. However, parts of the ventilation system can break, so it’s important to regularly perform a manual check to ensure everything is functioning correctly.

While it is important to keep birds warm in winter, it is also important that enough fresh air is introduced into the house to keep ammonia and moisture levels low. Once the cold air enters the house, negative pressure should be used to warm the air, then exhaust it, thereby picking up moisture and helping to dry the floor. Producers should consider the most efficient way that this can be achieved in their system.

In hot weather, large fans at the end of the house can push air movement through the house at more than 500 feet/minute. This fast air speed creates a wind chill that can drop the “feels-like” temperature by at least 10 °F. Other methods to keep the birds cool include evaporative cooling cells and foggers which create a fine mist over the birds. These need to be maintained well to avoid creating wet areas in the house. The water used in these systems should be good quality to avoid mineral build-up in the lines causing damage and introducing pathogens to the birds. More information on water quality can be found in our water quality ABF best practices post.

Back-up generators and emergency plans are essential for protecting birds and the farm from disastrous consequences in a power outage. Without adequate ventilation and air movement, the environment inside the house can become dangerous very quickly, in both cold and hot conditions. Houses are usually sealed tight to ensure efficient heating/cooling, but this means that humidity and temperature can increase very quickly during power failure, as well as CO2 levels and water vapor from the birds.

Providing an optimum poultry house environment with adequate ventilation, the right temperature and humidity for the birds’ age and low contaminants in the air is key for maximizing bird performance. Amlan is dedicated to developing next-generation technology to help poultry producers keep birds healthy and maintain productivity for life. Check our Education Center for other posts in our ABF production best practices series.

ABF Poultry Production Best Practice Series: House Environment and Biosecurity

Antibiotic-free poultry sanitation and hygiene infographic.

All poultry farms should maintain effective house sanitation and biosecurity practices to produce healthy and productive birds, but this is even more important when the goal is antibiotic-free (ABF) production. Here, we take a closer look at what our industry experts consider as best practices for house environment when producing ABF broilers, as part of our series on strategies for producing antibiotic-free poultry.

A Healthy Start to Life

Producing healthy flocks begins at the hatchery. It is important that the chick is provided a clean environment right from the start, and this includes while it is still in the egg. The hatchery should be kept clean, disinfected often and there should be no contamination on the egg pack. If in ovo vaccination is used, sanitary conditions are crucial to keep infection and 7-day mortality rates low. Keeping the chick’s stress low during transport and transition to the farm is also important for a healthy, productive bird.

Starting with a strong, healthy chick is important, as weak chicks are more likely to succumb to pathogens and have higher mortality rates. Once the chicks arrive at the house, they should immediately be provided with high-quality nutrients, which includes fresh, clean water as well as feed. Water quality best practices are discussed in another post that is part of our strategies for producing ABF poultry series.

Another important factor in producing a strong, healthy chick is a healthy breeder. A healthy breeder produces a better egg (e.g., superior shell quality) which means a safer start for the chick. To keep breeders healthy in a ABF system, feed additives can be used instead to ensure peak performance.

Effective Litter Management: Time Consuming but Essential

Litter management is critical to keeping birds healthy and productive and reducing disease challenges. The ideal litter has a depth of 3 to 4 inches and has low moisture and ammonia levels. When choosing an appropriate litter (e.g., pine shavings, rice hulls, hay, wheat straw), it is important to consider how well it absorbs moisture and if it can contaminate feeders easily.

In some cases, litter can be reused if any caked/wet litter is removed first. Wet litter can be prevented by managing water nipples, lines, pressure and height correctly and monitoring for leaks regularly. An effective ventilation system is also important for keeping litter dry, ammonia levels low and birds healthy. We will discuss the importance of air quality in a future ABF best practices post.

Our industry experts recommend allowing 14 days between batches to get the litter dried out. They also recommend windrowing (piling into rows) the litter during this time. While it is time expensive, windrowing heats the litter (it should be at least 130 °F or 54 °C for 3 to 4 days), reducing the pathogen load and infestation of insects such as darkling beetle, while allowing the surrounding floor to dry.

It’s also recommended that once a year the house is cleaned to the ground, disinfected, the floors salted, and dust removed as much as possible. Some producers may notice that the first batch of birds in the house after an annual cleanout does not perform as well, since the beneficial bacteria are also removed when the litter is completely removed.

Biosecurity Is Key

The biggest risk to introducing pathogens and disease to a flock is people, especially those responsible for the flock’s day-to-day management. To avoid infecting the flock, visitors to the farm should be limited and personal protective equipment should always be worn. This can include boots, mask, hair nets, coveralls and gloves and using footbaths between houses. Even though boots worn in the houses should be left at the farm, it is good practice to use disinfectant spray on shoes and floorboards when arriving at and leaving farms. Any shared equipment and the tires of vehicles should also be sprayed with disinfectant when moving between farms. Ideally, equipment that is used often should be purchased for and remain at each farm.

Rodents can also carry pathogens into the house and infect the flock. Even if the house appears sealed, rodents may still find a way in. Insects can also be an issue, particularly for long-lived birds (25 to 65 weeks). Therefore, it is advisable to have a pest control system in place. Wild birds like ducks and geese can also introduce pathogens (e.g., avian influenza) into the flock by contaminating open water sources (e.g., ponds) or through foot traffic.

Managing poultry house environmental conditions and biosecurity takes a lot of time and resources but is essential for keeping flocks healthy and production profitable. Amlan is dedicated to developing next-generation technology to help poultry producers keep birds healthy and maintain productivity for life. Download a helpful, printable guide that summarizes the above best practices here, and check our Education Center for other posts on our ABF production best practices series.

Intestinal Health Is Key for Maximizing Production Value and Efficiency

Computer-generated illustration of gut bacteria.

A healthy, functional gastrointestinal tract that defends against pathogens and their toxins is essential for achieving peak performance in poultry and livestock. Intestinal diseases in protein production cause billions of dollars in economic loss each year, so finding effective methods to proactively protect the intestinal environment is an important task for producers, particularly for antibiotic-free (ABF) systems. Understanding how intestinal function affects the production efficiency and overall health of poultry and livestock is the first step in finding solutions to support a healthy intestinal environment. Watch our educational animated video here or read below to learn more.

Intestinal Function and Anatomy

The intestines are covered with finger-like structures called villi that increase the surface area of the intestine and whose primary function is nutrient absorption (Figure 1). The villi and the underlying tissue are also home to vast numbers of immune cells. Lining the villi are enterocytes: cells that use microvilli to absorb nutrients from the intestinal lumen into the circulatory system.

Between the enterocytes are tight junctions that regulate intestinal permeability. The enterocytes form the one-cell-thick intestinal wall which, together with a mucus covering, act as a barrier between the lumen contents and the rest of the body. To function correctly, the enterocytes need to be healthy, properly nourished and energized.

Illustration of a healthy intestine.
Figure 1: Anatomy of a healthy intestine

Defend Against Pathogen Invasion

The intestine does more than aid digestion and absorption; it acts as a gatekeeper, protecting the body against harmful pathogens and their toxins. The mucus and enterocytes that line the intestine form a barrier and are the first line of defense against the external environment. Therefore, if the intestinal environment is unhealthy and not functioning correctly, it can have a negative impact on multiple systems in the body.

In normal production settings, birds and livestock are exposed to pathogens through feed and the environment. Some pathogens are destroyed by the acidic environment of the stomach; however, some survive and establish within the microbiota of the small intestine. An imbalanced intestinal environment can result in an overgrowth of pathogens, which triggers the response that can lead to enteric disease (e.g., necrotic enteritis) or prevents animals from reaching their maximum production potential.

Once established, virulent strains of bacteria can secrete potent toxins during rapid cellular growth and metabolism. Lipid-like toxins can also be released from bacterial cell walls when bacteria die, either naturally, from antibiotic use or due to the immune response. The toxins disrupt the tight junctions and trigger enterocyte death, causing breakdown of the protective intestinal barrier (Figure 2). The barrier breakdown impedes nutrient digestion and adsorption, limits organ function and allows toxins to enter the circulatory system.

Illustration of an unhealthy intestine.
Figure 2: A weakened intestinal barrier where bacteria and toxins have overcome the cellular defense mechanisms and weakened enterocytes cannot effectively function.

Natural Solutions to Maintain Intestinal Health

With the increase in antibiotic-free production systems, maintaining a healthy intestinal environment now requires a natural method to reduce the levels of pathogens in the intestinal environment. Amlan’s patented, natural mineral-based formulations, Varium® for poultry and NeoPrime® for swine, modify the intestinal environment by reducing pathogenic bacteria and their toxins, stimulating innate immune function and energizing enterocytes to create a strong intestinal barrier.

When Varium or NeoPrime are added to diets, pathogens and their toxins in the intestinal lumen are bound by Amlan’s proprietary, thermally activated mineral technology. The bound pathogens are then safely presented to the immune system via intestinal microfold (M) cells. Immune cells process these antigens and create more immune cells to naturally defend against invasion.

By presenting the bound antigens safely to the immune system before it is overwhelmed by high levels of pathogenic challenge, the immune system is thermally activated and prepared to mount a proper defense. After the pathogenic or toxin challenge is reduced, strengthening the epithelial cells that line the intestinal tract and keeping pathogens and toxins outside the body helps provide additional protection.

Maintaining a healthy intestinal environment is key to helping livestock and poultry perform to their maximum potential. Amlan can help, with next-generation mineral technology that reduces pathogenic challenges, strengthens the intestinal barrier and primes the immune system to naturally defend against disease. For more information, visit https://amlan.com/products/

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